{"id":140294,"date":"2022-06-15T11:20:51","date_gmt":"2022-06-15T11:20:51","guid":{"rendered":"https:\/\/stg.strategist1trial.com\/faqs\/"},"modified":"2026-01-08T17:11:06","modified_gmt":"2026-01-08T17:11:06","slug":"faqs","status":"publish","type":"page","link":"https:\/\/stg.strategist3trial.com\/en-ca\/faqs\/","title":{"rendered":"FAQs"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row row_height_percent=&#8221;100&#8243; back_color=&#8221;color-138503&#8243; back_image=&#8221;112255&#8243; back_repeat=&#8221;no-repeat&#8221; back_attachment=&#8221;scroll&#8221; back_position=&#8221;center center&#8221; parallax=&#8221;yes&#8221; overlay_alpha=&#8221;50&#8243; gutter_size=&#8221;4&#8243; column_width_percent=&#8221;100&#8243; shift_y=&#8221;0&#8243; z_index=&#8221;0&#8243; enable_bottom_divider=&#8221;default&#8221; bottom_divider_inv=&#8221;tilt&#8221; shape_bottom_invert=&#8221;yes&#8221; shape_bottom_h_use_pixel=&#8221;&#8221; shape_bottom_height=&#8221;100&#8243; shape_bottom_color=&#8221;color-xsdn&#8221; shape_bottom_opacity=&#8221;100&#8243; shape_bottom_index=&#8221;0&#8243; medium_visibility=&#8221;yes&#8221; mobile_visibility=&#8221;yes&#8221; row_name=&#8221;iphone&#8221; el_class=&#8221;gradient&#8221; uncode_shortcode_id=&#8221;111541&#8243; back_color_type=&#8221;uncode-palette&#8221; shape_bottom_color_type=&#8221;uncode-palette&#8221;][vc_column column_width_use_pixel=&#8221;yes&#8221; position_vertical=&#8221;middle&#8221; align_horizontal=&#8221;align_center&#8221; gutter_size=&#8221;3&#8243; style=&#8221;dark&#8221; overlay_alpha=&#8221;50&#8243; shift_x=&#8221;0&#8243; shift_y=&#8221;0&#8243; shift_y_down=&#8221;0&#8243; z_index=&#8221;0&#8243; medium_width=&#8221;7&#8243; align_mobile=&#8221;align_center_mobile&#8221; mobile_width=&#8221;0&#8243; css_animation=&#8221;bottom-t-top&#8221; animation_delay=&#8221;200&#8243; width=&#8221;1\/1&#8243; uncode_shortcode_id=&#8221;276875&#8243; column_width_pixel=&#8221;1000&#8243;][vc_custom_heading text_color=&#8221;color-681992&#8243; heading_semantic=&#8221;h1&#8243; text_font=&#8221;font-514338&#8243; text_weight=&#8221;300&#8243; sub_lead=&#8221;yes&#8221; sub_reduced=&#8221;yes&#8221; uncode_shortcode_id=&#8221;140228&#8243; text_color_type=&#8221;uncode-palette&#8221;]<span style=\"font-weight: 400\">Frequently Asked Questions<\/span>[\/vc_custom_heading][vc_custom_heading text_color=&#8221;color-196438&#8243; heading_semantic=&#8221;h1&#8243; text_font=&#8221;font-195745&#8243; text_size=&#8221;&#8221; text_weight=&#8221;600&#8243; sub_lead=&#8221;yes&#8221; sub_reduced=&#8221;yes&#8221; uncode_shortcode_id=&#8221;114728&#8243; text_color_type=&#8221;uncode-palette&#8221;]YOUR QUESTIONS, ANSWERED.[\/vc_custom_heading][vc_empty_space empty_h=&#8221;1&#8243;][vc_empty_space empty_h=&#8221;2&#8243;][\/vc_column][\/vc_row][vc_row row_height_percent=&#8221;100&#8243; back_color=&#8221;color-138503&#8243; back_image=&#8221;112249&#8243; back_repeat=&#8221;no-repeat&#8221; back_attachment=&#8221;fixed&#8221; back_position=&#8221;center bottom&#8221; overlay_alpha=&#8221;50&#8243; gutter_size=&#8221;4&#8243; column_width_percent=&#8221;100&#8243; shift_y=&#8221;0&#8243; z_index=&#8221;0&#8243; enable_bottom_divider=&#8221;default&#8221; bottom_divider_inv=&#8221;tilt&#8221; shape_bottom_invert=&#8221;yes&#8221; shape_bottom_h_use_pixel=&#8221;&#8221; shape_bottom_height=&#8221;100&#8243; shape_bottom_color=&#8221;color-xsdn&#8221; shape_bottom_opacity=&#8221;100&#8243; shape_bottom_index=&#8221;0&#8243; desktop_visibility=&#8221;yes&#8221; mobile_visibility=&#8221;yes&#8221; row_name=&#8221;iphone&#8221; el_class=&#8221;gradient&#8221; uncode_shortcode_id=&#8221;114217&#8243; back_color_type=&#8221;uncode-palette&#8221; shape_bottom_color_type=&#8221;uncode-palette&#8221;][vc_column column_width_use_pixel=&#8221;yes&#8221; position_vertical=&#8221;middle&#8221; align_horizontal=&#8221;align_center&#8221; gutter_size=&#8221;3&#8243; style=&#8221;dark&#8221; overlay_alpha=&#8221;50&#8243; shift_x=&#8221;0&#8243; shift_y=&#8221;0&#8243; shift_y_down=&#8221;0&#8243; z_index=&#8221;0&#8243; medium_width=&#8221;7&#8243; align_mobile=&#8221;align_center_mobile&#8221; mobile_width=&#8221;0&#8243; css_animation=&#8221;bottom-t-top&#8221; animation_delay=&#8221;200&#8243; width=&#8221;1\/1&#8243; uncode_shortcode_id=&#8221;276875&#8243; column_width_pixel=&#8221;1000&#8243;][vc_empty_space empty_h=&#8221;3&#8243;][vc_custom_heading text_color=&#8221;color-681992&#8243; heading_semantic=&#8221;h1&#8243; text_font=&#8221;font-514338&#8243; text_weight=&#8221;300&#8243; sub_lead=&#8221;yes&#8221; sub_reduced=&#8221;yes&#8221; uncode_shortcode_id=&#8221;166716&#8243; text_color_type=&#8221;uncode-palette&#8221;]<span style=\"font-weight: 400\">Frequently Asked Questions<\/span>[\/vc_custom_heading][vc_custom_heading text_color=&#8221;color-196438&#8243; heading_semantic=&#8221;h1&#8243; text_font=&#8221;font-195745&#8243; text_size=&#8221;&#8221; text_weight=&#8221;600&#8243; sub_lead=&#8221;yes&#8221; sub_reduced=&#8221;yes&#8221; uncode_shortcode_id=&#8221;105352&#8243; text_color_type=&#8221;uncode-palette&#8221;]YOUR QUESTIONS, ANSWERED.[\/vc_custom_heading][vc_empty_space empty_h=&#8221;1&#8243;][vc_empty_space empty_h=&#8221;5&#8243;][\/vc_column][\/vc_row][vc_row row_height_percent=&#8221;100&#8243; back_color=&#8221;color-138503&#8243; back_image=&#8221;112248&#8243; back_attachment=&#8221;scroll&#8221; back_position=&#8221;center center&#8221; overlay_alpha=&#8221;50&#8243; gutter_size=&#8221;4&#8243; column_width_percent=&#8221;100&#8243; shift_y=&#8221;0&#8243; z_index=&#8221;0&#8243; enable_bottom_divider=&#8221;default&#8221; bottom_divider_inv=&#8221;tilt&#8221; shape_bottom_invert=&#8221;yes&#8221; shape_bottom_h_use_pixel=&#8221;&#8221; shape_bottom_height=&#8221;100&#8243; shape_bottom_color=&#8221;color-xsdn&#8221; shape_bottom_opacity=&#8221;100&#8243; shape_bottom_index=&#8221;0&#8243; desktop_visibility=&#8221;yes&#8221; medium_visibility=&#8221;yes&#8221; row_name=&#8221;iphone&#8221; el_class=&#8221;gradient&#8221; uncode_shortcode_id=&#8221;308018&#8243; back_color_type=&#8221;uncode-palette&#8221; shape_bottom_color_type=&#8221;uncode-palette&#8221;][vc_column column_width_use_pixel=&#8221;yes&#8221; position_vertical=&#8221;middle&#8221; align_horizontal=&#8221;align_center&#8221; gutter_size=&#8221;3&#8243; style=&#8221;dark&#8221; overlay_alpha=&#8221;50&#8243; shift_x=&#8221;0&#8243; shift_y=&#8221;0&#8243; shift_y_down=&#8221;0&#8243; z_index=&#8221;0&#8243; medium_width=&#8221;7&#8243; align_mobile=&#8221;align_center_mobile&#8221; mobile_width=&#8221;0&#8243; css_animation=&#8221;bottom-t-top&#8221; animation_delay=&#8221;200&#8243; width=&#8221;1\/1&#8243; uncode_shortcode_id=&#8221;276875&#8243; column_width_pixel=&#8221;1000&#8243;][vc_empty_space empty_h=&#8221;2&#8243;][vc_custom_heading text_color=&#8221;color-681992&#8243; heading_semantic=&#8221;h1&#8243; text_font=&#8221;font-514338&#8243; text_size=&#8221;h4&#8243; text_weight=&#8221;300&#8243; sub_lead=&#8221;yes&#8221; sub_reduced=&#8221;yes&#8221; uncode_shortcode_id=&#8221;134194&#8243; text_color_type=&#8221;uncode-palette&#8221;]<span style=\"font-weight: 400\">Frequently Asked Questions<\/span>[\/vc_custom_heading][vc_custom_heading text_color=&#8221;color-196438&#8243; heading_semantic=&#8221;h1&#8243; text_font=&#8221;font-195745&#8243; text_weight=&#8221;600&#8243; sub_lead=&#8221;yes&#8221; sub_reduced=&#8221;yes&#8221; uncode_shortcode_id=&#8221;420235&#8243; text_color_type=&#8221;uncode-palette&#8221;]YOUR QUESTIONS, ANSWERED.[\/vc_custom_heading][vc_empty_space empty_h=&#8221;5&#8243;][\/vc_column][\/vc_row][vc_row row_height_percent=&#8221;100&#8243; override_padding=&#8221;yes&#8221; h_padding=&#8221;2&#8243; top_padding=&#8221;7&#8243; bottom_padding=&#8221;7&#8243; back_color=&#8221;color-xsdn&#8221; overlay_alpha=&#8221;50&#8243; gutter_size=&#8221;0&#8243; column_width_percent=&#8221;100&#8243; shift_y=&#8221;0&#8243; z_index=&#8221;0&#8243; top_divider=&#8221;step_1_2&#8243; desktop_visibility=&#8221;yes&#8221; mobile_visibility=&#8221;yes&#8221; changer_back_color=&#8221;yes&#8221; uncode_shortcode_id=&#8221;120331&#8243; back_color_type=&#8221;uncode-palette&#8221; row_name=&#8221;questions&#8221;][vc_column column_width_percent=&#8221;100&#8243; gutter_size=&#8221;5&#8243; overlay_alpha=&#8221;50&#8243; shift_x=&#8221;0&#8243; shift_y=&#8221;0&#8243; shift_y_down=&#8221;0&#8243; z_index=&#8221;0&#8243; medium_width=&#8221;0&#8243; mobile_width=&#8221;0&#8243; width=&#8221;1\/1&#8243; uncode_shortcode_id=&#8221;166430&#8243;][vc_row_inner limit_content=&#8221;&#8221;][vc_column_inner width=&#8221;1\/3&#8243;][vc_custom_heading text_color=&#8221;color-681992&#8243; text_size=&#8221;&#8221; sub_reduced=&#8221;yes&#8221; text_align=&#8221;text-left&#8221; text_serif=&#8221;yes&#8221; uncode_shortcode_id=&#8221;384218&#8243; text_color_type=&#8221;uncode-palette&#8221;]General Questions[\/vc_custom_heading][vc_empty_space empty_h=&#8221;2&#8243;][\/vc_column_inner][vc_column_inner width=&#8221;2\/3&#8243;][vc_custom_heading heading_semantic=&#8221;h3&#8243; text_size=&#8221;&#8221; sub_reduced=&#8221;yes&#8221; text_align=&#8221;text-left&#8221; text_serif=&#8221;yes&#8221; uncode_shortcode_id=&#8221;999729&#8243; subheading=&#8221;Your health will be monitored continuously throughout StrateGIST 3 Trial. Even if you do not directly benefit from participating in the trial, any information collected may help researchers learn more about the study drug IDRX-42 and about treating other adults with GIST in the future.&#8221;]What are the benefits of participating in StrateGIST 3?[\/vc_custom_heading][vc_custom_heading heading_semantic=&#8221;h3&#8243; text_size=&#8221;&#8221; sub_reduced=&#8221;yes&#8221; text_align=&#8221;text-left&#8221; text_serif=&#8221;yes&#8221; uncode_shortcode_id=&#8221;146860&#8243; subheading=&#8221;As with all medicines, there is a risk for side effects from the study drugs. However, your safety is our top priority. Your health will be closely monitored during the entire study. A special group of experts called the Data Monitoring Committee will also review data throughout the entire trial to make sure all participants are kept safe.&#8221;]Are their risks to participating in the trial?[\/vc_custom_heading][vc_custom_heading 1=&#8221;biopharmaceutical&#8221; 2=&#8221;company&#8221; 3=&#8221;IDRx,&#8221; 4=&#8221;Inc.&#8221; 5=&#8221;is&#8221; 6=&#8221;sponsoring&#8221; 7=&#8221;the&#8221; 8=&#8221;clinical&#8221; 9=&#8221;trial.&#8221; 10=&#8221;They&#8221; 11=&#8221;will&#8221; 12=&#8221;pay&#8221; 13=&#8221;the&#8221; 14=&#8221;study&#8221; 15=&#8221;doctor&#8221; 16=&#8221;and&#8221; 17=&#8221;site&#8221; 18=&#8221;staff&#8221; 19=&#8221;to&#8221; 20=&#8221;run&#8221; 21=&#8221;this&#8221; 22=&#8221;trial.&#8221; 23=&#8221;To&#8221; 24=&#8221;learn&#8221; 25=&#8221;more&#8221; 26=&#8221;about&#8221; 27=&#8221;IDRx,&#8221; 28=&#8221;visit&#8221; 29=&#8221;&#8221; 30=&#8221;href=&#8220;&#8220;https:\/\/www.idrx.com&#8220;&#8220;&gt;www.idrx.com&#8221; 31=&#8221;.&#8220;&#8221; heading_semantic=&#8221;h3&#8243; text_size=&#8221;&#8221; sub_reduced=&#8221;yes&#8221; text_align=&#8221;text-left&#8221; text_serif=&#8221;yes&#8221; uncode_shortcode_id=&#8221;148716&#8243;]Who is sponsoring StrateGIST 3 clinical trial?[\/vc_custom_heading][vc_column_text uncode_shortcode_id=&#8221;203685&#8243; css=&#8221;.vc_custom_1731516055759{margin-top: 10px !important;}&#8221;]<span style=\"font-weight: 400\">The biopharmaceutical company IDRx, Inc. is sponsoring the StrateGIST 3 clinical trial. They will pay the study doctors and site staff to run the trial. To learn more about IDRx, visit <\/span><a href=\"https:\/\/www.idrx.com\/\" target=\"_blank\" rel=\"noopener\">www.idrx.com<\/a>.[\/vc_column_text][vc_custom_heading heading_semantic=&#8221;h3&#8243; text_size=&#8221;&#8221; sub_reduced=&#8221;yes&#8221; text_align=&#8221;text-left&#8221; text_serif=&#8221;yes&#8221; uncode_shortcode_id=&#8221;150124&#8243; subheading=&#8221;The study treatment, site visits, and study-related tests will be paid for by the clinical trial sponsor, IDRx, Inc. and will not cost you anything. You will be reimbursed for reasonable study visit-related travel expenses.&#8221;]Will it cost me anything to be in the trial?[\/vc_custom_heading][vc_custom_heading heading_semantic=&#8221;h3&#8243; text_size=&#8221;&#8221; sub_reduced=&#8221;yes&#8221; text_align=&#8221;text-left&#8221; text_serif=&#8221;yes&#8221; uncode_shortcode_id=&#8221;430406&#8243; subheading=&#8221;Participation in a clinical trial is voluntary. If you decide to join and then change your mind, you can leave the trial at any time. Leaving the trial will not affect your regular medical care.&#8221;]What if I decide to join the trial and then change my mind?[\/vc_custom_heading][\/vc_column_inner][\/vc_row_inner][vc_row_inner limit_content=&#8221;&#8221;][vc_column_inner width=&#8221;1\/3&#8243;][vc_custom_heading text_color=&#8221;color-681992&#8243; text_size=&#8221;&#8221; sub_reduced=&#8221;yes&#8221; text_align=&#8221;text-left&#8221; text_serif=&#8221;yes&#8221; uncode_shortcode_id=&#8221;115706&#8243; text_color_type=&#8221;uncode-palette&#8221;]Study Drug Questions[\/vc_custom_heading][vc_empty_space empty_h=&#8221;2&#8243;][\/vc_column_inner][vc_column_inner width=&#8221;2\/3&#8243;][vc_custom_heading heading_semantic=&#8221;h3&#8243; text_size=&#8221;&#8221; sub_reduced=&#8221;yes&#8221; text_align=&#8221;text-left&#8221; text_serif=&#8221;yes&#8221; uncode_shortcode_id=&#8221;138330&#8243; subheading=&#8221;GIST is frequently caused by changes, or mutations, in a gene for a normal cell protein called KIT. These mutations lead to overactivation of KIT\u2014like a switch stuck in the on position\u2014 causing cancer cells to multiply.<\/p>\n<p>IDRX-42 is a tyrosine kinase inhibitor (TKI). TKIs stop or slow down KIT activity and the resulting growth of cancer cells. Other TKIs are used for GIST but may not work against all <i>KIT<\/i> mutations. IDRX-42 is designed to cover a broader range of <i>KIT<\/i> mutations.&#8221;]What is IDRX-42?[\/vc_custom_heading][vc_custom_heading heading_semantic=&#8221;h3&#8243; text_size=&#8221;&#8221; sub_reduced=&#8221;yes&#8221; text_align=&#8221;text-left&#8221; text_serif=&#8221;yes&#8221; uncode_shortcode_id=&#8221;172011&#8243; subheading=&#8221;As with all medicines, there is the possibility of side effects, which are unwanted or unintended effects of a medicine. Talk to the study doctor for more information on possible side effects. Your health will be closely monitored throughout the entire trial. Tell the study doctor if you notice any side effects or changes in your health.&#8221;]Are there any side effects from the study drugs?[\/vc_custom_heading][vc_custom_heading heading_semantic=&#8221;h3&#8243; text_size=&#8221;&#8221; sub_reduced=&#8221;yes&#8221; text_align=&#8221;text-left&#8221; text_serif=&#8221;yes&#8221; uncode_shortcode_id=&#8221;114741&#8243; subheading=&#8221;Yes, the study doctor will let you know which study treatment you are receiving.<\/p>\n<p>If I am assigned to receive sunitinib, will I have a chance to receive IDRX-42? If you are taking sunitinib and your cancer worsens, you may be able to switch the IDRX-42.&#8221;]Will I know if I am receiving IDRX-42 or sunitinib?[\/vc_custom_heading][\/vc_column_inner][\/vc_row_inner][vc_row_inner limit_content=&#8221;&#8221;][vc_column_inner width=&#8221;1\/3&#8243;][vc_custom_heading text_color=&#8221;color-681992&#8243; text_size=&#8221;&#8221; sub_reduced=&#8221;yes&#8221; text_align=&#8221;text-left&#8221; text_serif=&#8221;yes&#8221; uncode_shortcode_id=&#8221;123134&#8243; text_color_type=&#8221;uncode-palette&#8221;]StrateGIST 3 Questions[\/vc_custom_heading][vc_empty_space empty_h=&#8221;2&#8243;][\/vc_column_inner][vc_column_inner width=&#8221;2\/3&#8243;][vc_custom_heading heading_semantic=&#8221;h3&#8243; text_size=&#8221;&#8221; sub_reduced=&#8221;yes&#8221; text_align=&#8221;text-left&#8221; text_serif=&#8221;yes&#8221; uncode_shortcode_id=&#8221;699296&#8243; subheading=&#8221;You will be in the trial for up to 5.5 years. As with any clinical trial, you may stop participation at any time for any reason or no reason. IDRX, Inc. does not have any plans to provide IDRX-42 or any other study drugs or procedures to you after the end of the trial or if you have discontinued or have been withdrawn from the trial.&#8221;]How long will I be in the trial?[\/vc_custom_heading][vc_custom_heading heading_semantic=&#8221;h3&#8243; text_size=&#8221;&#8221; sub_reduced=&#8221;yes&#8221; text_align=&#8221;text-left&#8221; text_serif=&#8221;yes&#8221; uncode_shortcode_id=&#8221;127156&#8243; subheading=&#8221;If you qualify for the trial, you will be placed by chance into a group to receive either IDRX-42 or sunitinib, a treatment approved in some countries for the type of GIST being studied.&#8221;]What study treatment will I receive?[\/vc_custom_heading][vc_custom_heading heading_semantic=&#8221;h3&#8243; text_size=&#8221;&#8221; sub_reduced=&#8221;yes&#8221; text_align=&#8221;text-left&#8221; text_serif=&#8221;yes&#8221; uncode_shortcode_id=&#8221;514493&#8243; subheading=&#8221;IDRX-42 comes as tablets that you will take by mouth with water (with or without food). You will take IDRX-42 once a day as directed by the study doctor. You will keep taking IDRX-42 for as long as your cancer is not getting worse and you are tolerating treatment.&#8221;]How do I take IDRX-42?[\/vc_custom_heading][vc_custom_heading heading_semantic=&#8221;h3&#8243; text_size=&#8221;&#8221; sub_reduced=&#8221;yes&#8221; text_align=&#8221;text-left&#8221; text_serif=&#8221;yes&#8221; uncode_shortcode_id=&#8221;355188&#8243; subheading=&#8221;Sunitinib comes as capsules that you will take by mouth with water (with or without food). Sunitinib is taken once a day for 28 days at a time, followed by a 14-day break, unless otherwise instructed. You will keep taking sunitinib for as long as your cancer is not getting worse and you are tolerating treatment. If your cancer worsens while taking sunitinib, you may be able to switch to IDRX-42.&#8221;]How do I take sunitinib?[\/vc_custom_heading][vc_custom_heading heading_semantic=&#8221;h3&#8243; text_size=&#8221;&#8221; sub_reduced=&#8221;yes&#8221; text_align=&#8221;text-left&#8221; text_serif=&#8221;yes&#8221; uncode_shortcode_id=&#8221;700478&#8243;]What clinical trial sites are participating in StrateGIST 3?[\/vc_custom_heading][vc_column_text uncode_shortcode_id=&#8221;480045&#8243; css=&#8221;.vc_custom_1732655988927{margin-top: 10px !important;}&#8221;]Click <a href=\"\/#location\">here<\/a> for a list of participating sites and to find a location near you.[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row row_height_percent=&#8221;100&#8243; override_padding=&#8221;yes&#8221; h_padding=&#8221;2&#8243; top_padding=&#8221;7&#8243; bottom_padding=&#8221;7&#8243; back_color=&#8221;color-xsdn&#8221; back_image=&#8221;112276&#8243; back_attachment=&#8221;fixed&#8221; overlay_alpha=&#8221;50&#8243; gutter_size=&#8221;0&#8243; column_width_percent=&#8221;100&#8243; shift_y=&#8221;0&#8243; z_index=&#8221;0&#8243; top_divider=&#8221;step_1_2&#8243; medium_visibility=&#8221;yes&#8221; changer_back_color=&#8221;yes&#8221; uncode_shortcode_id=&#8221;111832&#8243; back_color_type=&#8221;uncode-palette&#8221; row_name=&#8221;questions&#8221;][vc_column column_width_percent=&#8221;100&#8243; gutter_size=&#8221;5&#8243; overlay_alpha=&#8221;50&#8243; shift_x=&#8221;0&#8243; shift_y=&#8221;0&#8243; shift_y_down=&#8221;0&#8243; z_index=&#8221;0&#8243; medium_width=&#8221;0&#8243; mobile_width=&#8221;0&#8243; width=&#8221;1\/1&#8243; uncode_shortcode_id=&#8221;166430&#8243;][vc_row_inner limit_content=&#8221;&#8221;][vc_column_inner width=&#8221;1\/3&#8243;][vc_custom_heading text_color=&#8221;color-681992&#8243; text_size=&#8221;&#8221; sub_reduced=&#8221;yes&#8221; text_align=&#8221;text-left&#8221; text_serif=&#8221;yes&#8221; uncode_shortcode_id=&#8221;384218&#8243; text_color_type=&#8221;uncode-palette&#8221;]General Questions[\/vc_custom_heading][vc_empty_space empty_h=&#8221;2&#8243;][\/vc_column_inner][vc_column_inner width=&#8221;2\/3&#8243;][vc_custom_heading heading_semantic=&#8221;h3&#8243; text_size=&#8221;&#8221; sub_reduced=&#8221;yes&#8221; text_align=&#8221;text-left&#8221; text_serif=&#8221;yes&#8221; uncode_shortcode_id=&#8221;207094&#8243; subheading=&#8221;No benefits are guaranteed, however, your health will be monitored continuously throughout the StrateGIST 3 Trial. Even if you do not directly benefit from participating in the trial, any information collected may help researchers learn more about the investigational study drug and about treating other adults with GIST in the future.&#8221;]What are the benefits of participating in StrateGIST 3?[\/vc_custom_heading][vc_custom_heading heading_semantic=&#8221;h3&#8243; text_size=&#8221;&#8221; sub_reduced=&#8221;yes&#8221; text_align=&#8221;text-left&#8221; text_serif=&#8221;yes&#8221; uncode_shortcode_id=&#8221;134402&#8243; subheading=&#8221;As with all medicines, there is a risk for side effects from the study drugs. Your health will be closely monitored during the entire study. Talk to the study doctor for more information on possible risks.&#8221;]Are there risks to participating in the trial?[\/vc_custom_heading][vc_custom_heading 1=&#8221;biopharmaceutical&#8221; 2=&#8221;company&#8221; 3=&#8221;IDRx,&#8221; 4=&#8221;Inc.&#8221; 5=&#8221;is&#8221; 6=&#8221;sponsoring&#8221; 7=&#8221;the&#8221; 8=&#8221;clinical&#8221; 9=&#8221;trial.&#8221; 10=&#8221;They&#8221; 11=&#8221;will&#8221; 12=&#8221;pay&#8221; 13=&#8221;the&#8221; 14=&#8221;study&#8221; 15=&#8221;doctor&#8221; 16=&#8221;and&#8221; 17=&#8221;site&#8221; 18=&#8221;staff&#8221; 19=&#8221;to&#8221; 20=&#8221;run&#8221; 21=&#8221;this&#8221; 22=&#8221;trial.&#8221; 23=&#8221;To&#8221; 24=&#8221;learn&#8221; 25=&#8221;more&#8221; 26=&#8221;about&#8221; 27=&#8221;IDRx,&#8221; 28=&#8221;visit&#8221; 29=&#8221;&#8221; 30=&#8221;href=&#8220;&#8220;https:\/\/www.idrx.com&#8220;&#8220;&gt;www.idrx.com&#8221; 31=&#8221;.&#8220;&#8221; heading_semantic=&#8221;h3&#8243; text_size=&#8221;&#8221; sub_reduced=&#8221;yes&#8221; text_align=&#8221;text-left&#8221; text_serif=&#8221;yes&#8221; uncode_shortcode_id=&#8221;657637&#8243;]Who is sponsoring the StrateGIST 3 clinical trial?[\/vc_custom_heading][vc_column_text uncode_shortcode_id=&#8221;864541&#8243; css=&#8221;.vc_custom_1767891979806{margin-top: 10px !important;}&#8221;]The global biopharmaceutical company provides funding to the study site to conduct the trial. This funding supports the work of the research team, including doctors and site staff. [\/vc_column_text][vc_custom_heading heading_semantic=&#8221;h3&#8243; text_size=&#8221;&#8221; sub_reduced=&#8221;yes&#8221; text_align=&#8221;text-left&#8221; text_serif=&#8221;yes&#8221; uncode_shortcode_id=&#8221;122123&#8243; subheading=&#8221;You do not have to pay to take part in this study. The study treatment and study-related tests will be paid for by the clinical trial sponsor. You may be reimbursed for reasonable study visit-related travel expenses.&#8221;]Will it cost me anything to be in the trial?[\/vc_custom_heading][vc_custom_heading heading_semantic=&#8221;h3&#8243; text_size=&#8221;&#8221; sub_reduced=&#8221;yes&#8221; text_align=&#8221;text-left&#8221; text_serif=&#8221;yes&#8221; uncode_shortcode_id=&#8221;430406&#8243; subheading=&#8221;Participation in a clinical trial is voluntary. If you decide to join and then change your mind, you can leave the trial at any time. Leaving the trial will not affect your regular medical care.&#8221;]What if I decide to join the trial and then change my mind?[\/vc_custom_heading][\/vc_column_inner][\/vc_row_inner][vc_row_inner limit_content=&#8221;&#8221;][vc_column_inner width=&#8221;1\/3&#8243;][vc_custom_heading text_color=&#8221;color-681992&#8243; text_size=&#8221;&#8221; sub_reduced=&#8221;yes&#8221; text_align=&#8221;text-left&#8221; text_serif=&#8221;yes&#8221; uncode_shortcode_id=&#8221;115706&#8243; text_color_type=&#8221;uncode-palette&#8221;]Study Drug Questions[\/vc_custom_heading][vc_empty_space empty_h=&#8221;2&#8243;][\/vc_column_inner][vc_column_inner width=&#8221;2\/3&#8243;][vc_custom_heading heading_semantic=&#8221;h3&#8243; text_size=&#8221;&#8221; sub_reduced=&#8221;yes&#8221; text_align=&#8221;text-left&#8221; text_serif=&#8221;yes&#8221; uncode_shortcode_id=&#8221;185180&#8243; subheading=&#8221;GIST is frequently caused by changes, or mutations, in a gene for a normal cell protein called KIT. These mutations lead to overactivation of KIT\u2014like a switch stuck in the on position\u2014causing cancer cells to multiply.<\/p>\n<p>The investigational study drug is a tyrosine kinase inhibitor (TKI). TKIs stop or slow down KIT activity and the resulting growth of cancer cells. Other TKIs are used for GIST but may not work against all KIT mutations. The investigational study drug is designed to cover a broader range of KIT mutations.&#8221; text_color_type=&#8221;uncode-palette&#8221; text_color_solid=&#8221;#ff0000&#8243;]What is the investigational study drug?[\/vc_custom_heading][vc_custom_heading heading_semantic=&#8221;h3&#8243; text_size=&#8221;&#8221; sub_reduced=&#8221;yes&#8221; text_align=&#8221;text-left&#8221; text_serif=&#8221;yes&#8221; uncode_shortcode_id=&#8221;172011&#8243; subheading=&#8221;As with all medicines, there is the possibility of side effects, which are unwanted or unintended effects of a medicine. Talk to the study doctor for more information on possible side effects. Your health will be closely monitored throughout the entire trial. Tell the study doctor if you notice any side effects or changes in your health.&#8221;]Are there any side effects from the study drugs?[\/vc_custom_heading][vc_custom_heading heading_semantic=&#8221;h3&#8243; text_size=&#8221;&#8221; sub_reduced=&#8221;yes&#8221; text_align=&#8221;text-left&#8221; text_serif=&#8221;yes&#8221; uncode_shortcode_id=&#8221;954652&#8243; subheading=&#8221;Yes, the study doctor will let you know which study treatment you are receiving.&#8221;]Will I know if I am receiving the investigational study drug or sunitinib?[\/vc_custom_heading][\/vc_column_inner][\/vc_row_inner][vc_row_inner limit_content=&#8221;&#8221;][vc_column_inner width=&#8221;1\/3&#8243;][vc_custom_heading text_color=&#8221;color-681992&#8243; text_size=&#8221;&#8221; sub_reduced=&#8221;yes&#8221; text_align=&#8221;text-left&#8221; text_serif=&#8221;yes&#8221; uncode_shortcode_id=&#8221;123134&#8243; text_color_type=&#8221;uncode-palette&#8221;]StrateGIST 3 Questions[\/vc_custom_heading][vc_empty_space empty_h=&#8221;2&#8243;][\/vc_column_inner][vc_column_inner width=&#8221;2\/3&#8243;][vc_custom_heading heading_semantic=&#8221;h3&#8243; text_size=&#8221;&#8221; sub_reduced=&#8221;yes&#8221; text_align=&#8221;text-left&#8221; text_serif=&#8221;yes&#8221; uncode_shortcode_id=&#8221;161518&#8243; subheading=&#8221;You will be in the trial for up to 5 years. As with any clinical trial, you may stop participation at any time for any reason or no reason.&#8221;]How long will I be in the trial?[\/vc_custom_heading][vc_custom_heading heading_semantic=&#8221;h3&#8243; text_size=&#8221;&#8221; sub_reduced=&#8221;yes&#8221; text_align=&#8221;text-left&#8221; text_serif=&#8221;yes&#8221; uncode_shortcode_id=&#8221;206355&#8243; subheading=&#8221;If you qualify for the trial, you will be placed by chance into a group to receive either the investigational study drug or sunitinib, a treatment approved in some countries for the type of GIST being studied. At the end of the study, if you qualify, the clinical trial sponsor may provide access to the investigational study drug via a separate access program depending on local regulations.&#8221;]What study treatment will I receive?[\/vc_custom_heading][vc_custom_heading heading_semantic=&#8221;h3&#8243; text_size=&#8221;&#8221; sub_reduced=&#8221;yes&#8221; text_align=&#8221;text-left&#8221; text_serif=&#8221;yes&#8221; uncode_shortcode_id=&#8221;197910&#8243; subheading=&#8221;The investigational study drug comes as tablets that you will take by mouth with water (with or without food). You will take the investigational study drug once a day as directed by the study doctor. You will keep taking the investigational study drug for as long as your cancer is not getting worse and you are tolerating treatment.&#8221;]How do I take the investigational study drug?[\/vc_custom_heading][vc_custom_heading heading_semantic=&#8221;h3&#8243; text_size=&#8221;&#8221; sub_reduced=&#8221;yes&#8221; text_align=&#8221;text-left&#8221; text_serif=&#8221;yes&#8221; uncode_shortcode_id=&#8221;152983&#8243; subheading=&#8221;Sunitinib comes as capsules that you will take by mouth with water (with or without food). Sunitinib is taken once a day for 28 days at a time, followed by a 14-day break, unless otherwise instructed. You will keep taking sunitinib for as long as your cancer is not getting worse and you are tolerating treatment.&#8221;]How do I take sunitinib?[\/vc_custom_heading][vc_custom_heading heading_semantic=&#8221;h3&#8243; text_size=&#8221;&#8221; sub_reduced=&#8221;yes&#8221; text_align=&#8221;text-left&#8221; text_serif=&#8221;yes&#8221; uncode_shortcode_id=&#8221;700478&#8243;]What clinical trial sites are participating in StrateGIST 3?[\/vc_custom_heading][vc_column_text uncode_shortcode_id=&#8221;480045&#8243; css=&#8221;.vc_custom_1732655988927{margin-top: 10px !important;}&#8221;]Click <a href=\"\/#location\">here<\/a> for a list of participating sites and to find a location near you.[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>[vc_row row_height_percent=&#8221;100&#8243; back_color=&#8221;color-138503&#8243; back_image=&#8221;112255&#8243; back_repeat=&#8221;no-repeat&#8221; back_attachment=&#8221;scroll&#8221; back_position=&#8221;center center&#8221; parallax=&#8221;yes&#8221; overlay_alpha=&#8221;50&#8243; gutter_size=&#8221;4&#8243; column_width_percent=&#8221;100&#8243; shift_y=&#8221;0&#8243; z_index=&#8221;0&#8243; enable_bottom_divider=&#8221;default&#8221; bottom_divider_inv=&#8221;tilt&#8221; shape_bottom_invert=&#8221;yes&#8221; shape_bottom_h_use_pixel=&#8221;&#8221; shape_bottom_height=&#8221;100&#8243; shape_bottom_color=&#8221;color-xsdn&#8221; [&hellip;]<\/p>\n","protected":false},"author":4,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-140294","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/stg.strategist3trial.com\/en-ca\/wp-json\/wp\/v2\/pages\/140294","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/stg.strategist3trial.com\/en-ca\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/stg.strategist3trial.com\/en-ca\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/stg.strategist3trial.com\/en-ca\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/stg.strategist3trial.com\/en-ca\/wp-json\/wp\/v2\/comments?post=140294"}],"version-history":[{"count":0,"href":"https:\/\/stg.strategist3trial.com\/en-ca\/wp-json\/wp\/v2\/pages\/140294\/revisions"}],"wp:attachment":[{"href":"https:\/\/stg.strategist3trial.com\/en-ca\/wp-json\/wp\/v2\/media?parent=140294"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}